|USE OF 20 TU RT 23 AND 5 TU BATTEY ANTIGEN FOR ESTIMATION
OF PREVALENCE OF NON-SPECIFIC TUBERCULIN SENSITIVITY
|GD Gothi, AK Chakraborty, MJ Jayalakshmi & KT Ganapathy:
Indian J Med Res 1977, 66, 389-97.
Estimates of prevalence of non-specific tuberculin
sensitivity in south Indian population are based on studies using
large doses of tuberculin prepared from Mycobacterium tuberculosis.
In the present study, comparison of tuberculin test done on 2168
children aged 0-9 years with 20 TU RT 23 and 5 TU Battey antigen,
belonging to rural areas, have been done. The distribution of induration
to 20 TU RT 23 test has been compared to that of 5 TU Battey test,
to see whether estimates of prevalence of non- specific tuberculin
sensitivity based on the former could be compared with those based
on tests with antigen derived from other mycobacteria.
It was seen that distributions of reactions, mean
size of indurations as well as percentages of positive reactors
to either test were not significantly different in the two randomly
selected groups i.e., one tested with Battey antigen and the other
with 20 TU RT 23. The prevalence of non-specific sensitivity in
0-4 years age group based on Battey test was 18.4 per cent and that
with 20 TU test, 16.6 per cent. In the age group 5-9 years corresponding
rates were 54.2 and 60.1 per cent. From these observations, it is
suggested that if other antigens are not available, 20 TU RT 23
could be used for estimation of non-specific sensitivity.
|KEY WORDS: BATTEY ANTIGEN, PREVALENCE, NON SPECIFIC