|RESULTS OF TREATMENT WITH A SHORT COURSE CHEMOTHERAPY
REGIMEN USED UNDER FIELD CONDITIONS IN DISTRICT TUBERCULOSIS PROGRAMME
|K Chaudhuri, P Jagota & N Parimala: Indian J
TB 1993, 40, 83-89.
The treatment results of an unsupervised Short
Course Chemotherapy (SCC) regimen used under conditions of District
Tuberculosis Programme (DTP) are presented. The District Tuberculosis
Centre (DTC), Kolar and six of its Peripheral Health Institutions
(PHIs) formed the study area. No extra efforts except ensuring of
adequate availability of drugs at the participating centres were
made to obtain patients' compliance. In all, 584 smear positive
tuberculosis patients were diagnosed during the study period but
28.3% of the patients could not be initiated on treatment with the
chosen self administered SCC regimen -2EHRZ/6TH(EH).
Of the 382 put on treatment, only 33.2% completed
over 75% drug collections in both intensive and continuation phases.
The pattern of treatment compliance did not vary with the place
of treatment, i.e. DTC or PHI. Irrespective of treatment compliance,
nearly 72-77% of the patients attained smear negative status at
the end of the period of treatment, there being no difference between
PHI and DTC. However, deaths were higher in the PHI patients. This
could be attributed to a significantly higher proportion of aged
patients taking treatment at PHI than at DTC. Considering death
as an unfavourable outcome, overall favourable response was 65.9%.
Patients with drug sensitive bacilli had a higher rate of culture
negativity (70%), as compared to those with drug resistant bacilli
(48%). It was concluded that unsupervised SCC could give encouraging
results in a DTP setting, provided adequate drug supply was ensured.
|KEY WORDS: SCC, CONTROL PROGRAMME, OPERATIONAL