EPIDEMIOLOGY <<Back
 
 
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SOME EPIDEMIOLOGICAL ASPECTS OF TUBERCULOUS DISEASE AND INFECTION IN PAEDIATRIC AGE GROUP IN A RURAL COMMUNITY
GD Gothi, SS Nair & Pyare Lal: Indian Paediatrics 1971, 8, 186-94.

The prevalence and incidence rates of tuberculous infection and disease in the community are known in the age group 10 years and above from several surveys carried out so far. The present paper provides various parameters of tuberculosis in particular in the pediatric age group. A random sample of 119 villages in 3 taluks of Bangalore district were surveyed 4 times from May 1961 to July 1968 at intervals of 18 months, 3 years and 5 years of the initial survey. Tuberculin test was done for the entire available population with 1 TU PPD RT 23 with Tween 80, and 70mm X-ray for all available persons aged 5 years and above. Two samples of sputum were obtained from the X-ray abnormals, and examined by smear and culture.

It was found that prevalence of infection increased with age from 2.1% at 0-4 year age group to 16.5% at 10-14 year age group, compared to 47% at 15 years and above age group. Prevalence of disease in 5-14 year age group was considerably lower than in age group 15 years or more. Tuberculosis morbidity increased with the size of tuberculin reaction and it was high among children with reaction 20mm or more. Incidence of infection increased with age from 0.9% per year in age group 0-4 years to 2.8% per year among that of 15 years and above. Incidence of disease also showed the same phenomenon-, rising from 0.5% in age group 5-9 to 4% per year in the age group 15 years and above. There were 10 sputum positive cases in 5-14 years of age in first survey, of them, 8 became negative and one died. While from among 152 cases in 15 years and above age group, 48 became negative, 72 died and 32 remained positive. The fate of cases of pulmonary tuberculosis in 5-14 years age was not as serious as in 15 years and above age group. The survey had no means of examining miliary and meningeal tuberculosis.

Children as well as adults with larger reaction of 20mm or more to tuberculin test had higher mortality. This could be considered due to tuberculous infection after taking into account death due to non- tuberculous reasons in both the infected and uninfected groups. Use of chemoprophylaxis might be considered for those who give history of contact with open cases and have tuberculin reaction size 20mm or more.

KEYWORDS: CHILDREN, RURAL COMMUNITY, PREVALANCE, INCIDENCE, INFECTION, DISEASE, TUBERCULIN, INDURATION SIZE, MORTALITY, CHEMOPROPHYLAXIS.
 
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