The author presents a few selected topics for discussion expected to assist in the future formulation of strategies against the spread of TB. One such topic is demographic changes. In most developing countries, with constant age-specific rates, increasing population and a relative increase of the older age groups are expected to lead to an increase in the absolute number of TB cases, as illustrated with a simulation. The consequences of the fact that TB services are reflections of the health services which, in turn, reflect the general public services in the community and, that TB is closely related to the prevailing socio-economic conditions are discussed in detail. Also, it is suggested that the immediate and impressive successes of the reductionistic medicine led to an underestimation of the importance of the general living conditions in the generation of health.