The study examined the clinical profile of five hundred TB patients admitted to the Rajan Babu TB Hospital, Delhi and determined the clinical and socio-economic factors important in hospitalization, default and failure of therapy. An attempt was also made to judge the health awareness in these patients and from that the success or failure of the health education programme. It was found that the percentage of cases who had relapsed or who were drug failures was quite high in hospitalized patients. Socio-economic factors were solely or partially responsible for the patients seeking admission in almost 20% of the cases. These factors as well as lack of education and proper motivation were responsible for drug default and subsequent failure in a large number of cases. Health awareness was quite low even in patients who had stayed in the hospital for a prolonged period pointing towards a failure of health education.