To study the psycho-social variations of hospitalized TB patients, fifty percent of the population of the TB Sanatorium named Hermitage, of Sangrur District in Punjab, was selected. The subjects responded to the Structured Interview Schedule, a Physician's Rating Scale and objective-type psychological tests. The findings revealed that the peak age of the patients was in the range of 25-45 years; that most of the population of that Sanatorium was illiterate, and their socio-economic status was poor. Eighty-two percent of the patients came from the countryside; 77.5 were married and 84% among them had 1-7 children. Sixty-five percent of the patients had been ill for less than two years. About 56% of the male patients had a habit of drinking. Only 13% of the patients had disturbed family relations. No correlation was found between the patients' attitude towards their illness and the physician's rating about the severity of their illness. The Psychological Tests indicated that TB patients did not have different neurotic scores when compared with patients with other chest diseases.